Exposure route
Dimethyl phthalate can be absorbed into the body through the gastrointestinal tract, respiratory tract and skin.
Toxicity threshold
Threshold: 5mg/m3 (time weighted average) (American Conference of Governmental Industrial Hygienists, 2005). There is no standard for the maximum allowable concentration.
Acute toxicity: Rat oral, LD506 900 mg/kg; mouse oral 7 200mg/kg; rabbit oral 4 400mg/kg; cat inhalation 9 300 mg/m3x6.5h lethal; rat inhalation, half Lethal concentration LC505 490mg/m3; mice inhaled 4 350 mg/m3.
Biological effect
In vivo and in vitro effects
It is a low-toxicity category. Oral 4%-8% (feeding) of rats had a slight effect on growth, and the 8% diet group also had chronic renal effects. Effect on skin and eyes: Applying this product to rabbit skin does not cause irritation, but it can be absorbed. The LD50 of one coating>10mL/kg, and the LD50 of multiple coatings (after 90d)>4mL/kg.
Human body effect
Health hazards: Large doses can cause anesthesia, inhibit the nerve center, and cause sleepiness or coma. Mistake can cause gastrointestinal irritation, central nervous system depression, paralysis, and lower blood pressure. Human contact may cause polyneuritis. Instillation into human eyes can cause chemical burns. No skin irritation and allergies occurred. For humans, there are records of acute poisoning of this product due to oral administration. Workers engaged in the production of phthalate plasticizers may suffer from polyneuritis.
Human protection
Provide good natural ventilation conditions. Generally, no protection is needed, but under special circumstances, a gas mask should be worn. Wear safety glasses and work clothes when necessary. Generally, your hands do not need special protection. When there is a high concentration of this product in the air, wear an industrial A-type gas mask, and use a filter when there is aerosol. Adopt filter type A gas mask. When synthesizing and applying this product, especially when heating this product or the plastic containing this product, it should be sealed to prevent the escape of steam and aerosol. Smoking is strictly prohibited at the work site, and good hygiene practices are maintained.
Leakage emergency treatment
Cut off the fire source. Emergency personnel wear self-contained breathing apparatus and work clothes. Stop leaks while ensuring safety. Mix and absorb with sand or other non-combustible adsorbents, then collect and transport to the waste disposal site, or burn on the spot if safety is ensured. If there is a large amount of leakage, use the embankment to contain it, and then collect, transfer, recycle or dispose of it after harmless treatment.
Disposal method
Waste disposal method: It is recommended to use incineration for disposal.
Fire fighting methods
Use water spray, foam, carbon dioxide, dry powder, sand to extinguish the fire.